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Age-dependent changes in B lymphocyte development in man and mouse

P Ghia1, F Melchers, A G Rolink

  • 1Laboratorio di Immunologia Oncologica, Istituto per la Ricerca e la Cura del Cancro, Candiolo, Italy.

Experimental Gerontology
|April 18, 2000
PubMed

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Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...