[Positive effect of falbamate therapy in a boy with refractory epilepsy]
E Szczepanik1, M Pakszys, G Rusek
1Klinika Neurologii Dzieci i Młodziezy.
Abstract:
One of the most important achievement of contemporary epileptology has been a concept of epileptic syndromes. According to the Commission on Classification and Terminology of the International League Against Epilepsy there are many epileptic syndromes which differ from each other not only by prognosis but also by reaction to pharmacotherapy. Nevertheless the differentation between the some of epileptic syndromes may be difficult in spite of quite precise clinical and electrophysiological criteria. Good example of this problem may be the course of disease of the boy who is now eleven years old. His refractory epilepsy which started 7 years ago shares symptoms and signs of both epilepsy with myoclonic-astatic seizures (Doose Syndrome) and Lennox-Gastaut Syndrome. Felbamate therapy was consider to be the turning-point in both therapeutic and diagnostic meaning.
Related Concept Videos
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
Electroconvulsive Therapy


