Related Experiment Video
Updated: Oct 16, 2026

Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Children with congenital diaphragmatic hernia are at risk for lower levels of cognitive functioning and increased
N H Bouman1, H M Koot, D Tibboel
1Department of Child and Adolescent Psychiatry, Sophia Children's Hospital, Erasmus University Rotterdam, The Netherlands.
Insights
Children with Congenital Diaphragmatic Hernia (CDH) often experience cognitive, learning, emotional, and behavioral challenges. This study highlights the need for ongoing support and research into their long-term well-being.
Area of Science:
- Pediatric Medicine
- Developmental Psychology
- Clinical Research
Background:
- Congenital Diaphragmatic Hernia (CDH) is a serious birth defect impacting infant development.
- Previous research suggested Extra Corporeal Membrane Oxygenation (ECMO) treatment correlates with lower cognitive function in CDH patients.
- The long-term psychosocial functioning of children with CDH requires further investigation.
Purpose of the Study:
- To assess the physical, psychological, and social functioning of children with CDH.
- To evaluate cognitive abilities, school performance, and emotional/behavioral health in this population.
- To compare the functioning of CDH children with the general population.
Main Methods:
- Standardized assessment procedures were used to evaluate 11 children aged 8-12 with CDH.
- Data collected included physical health, IQ scores, school level, and parent/teacher/child-reported emotional and behavioral problems.
- Psychosocial functioning was further explored through interviews with children and parents.
Main Results:
- Most children exhibited good physical health, with half experiencing minor issues like bronchial hyperreactivity.
- Children with CDH had a mean IQ 15 points below the norm, with only 6 at expected school level.
- Increased emotional, behavioral, and depressive problems were reported by children, parents, and teachers compared to the general population.
Conclusions:
- Children with CDH demonstrate greater cognitive, learning, emotional, and behavioral challenges than their peers.
- This study could not confirm if lower cognitive function is solely linked to ECMO treatment, as no ECMO-treated children were included.
- Further longitudinal studies are essential to understand the long-term psychological and social outcomes for children with CDH.
Abstract:
The physical, psychological, and social functioning of 11 children aged 8 to 12 years with Congenital Diaphragmatic Hernia (CDH) was assessed with several standardized assessment procedures. Physically, most children functioned well at follow-up with half of the children showing minor physical problems such as bronchial hyperreactivity. The mean IQ of the children was 15 points (1 SD) below the norm of 100. Only 6 children were at expected school level. The children showed more emotional and behavioral problems than in the general population as reported by parents and teachers. The children themselves reported more depressive problems, but not a lower self-esteem than children in the general population. These results were confirmed by the results of interviews with parents and children concerning psychosocial functioning. It is concluded that children with CDH show more cognitive and learning problems and increased rates of emotional and behavioral problems compared to children in the general population. Since no children treated with Extra Corporeal Membrane Oxygenation (ECMO) were involved in this study, the earlier reports that lower cognitive functioning is limited to children with CDH treated with ECMO can not be confirmed by this study. Considering the results of this study, there is a need for further follow-up studies concerning the long-term psychological and social functioning of children with CDH.
Related Concept Videos
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Socioemotional Development during Infancy
Primary Temperament Types
Stella Chess...
Intellectual Disability
Oppositional Defiant Disorder
Diagnostic Criteria and...
Learning Disabilities
Dyslexia
Dyslexia is a...
Information Processing Approach
