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Related Experiment Videos

Transient visual loss after licorice ingestion.

K R Dobbins1, R F Saul

  • 1Department of Ophthalmology, Penn State Geisinger Medical Center, Danville, Pennsylvania, USA.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
|April 19, 2000
PubMed
Summary

Ingesting large amounts of licorice can cause temporary vision loss and visual disturbances. This is linked to licorice

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Area of Science:

  • Ophthalmology
  • Neurology
  • Pharmacology

Background:

  • Transient visual loss and aberrations can have various causes.
  • Licorice consumption is a potential, previously undescribed, etiological factor.

Observation:

  • A case series of five patients presented with transient visual symptoms.
  • All patients reported consuming significant quantities of licorice (0.25-2 lbs).
  • Two patients experienced documented visual loss via visual acuity and visual field testing.

Findings:

  • Licorice derivatives, specifically glycyrrhetinic acid, enhance vasoconstrictor action.
  • This mechanism is hypothesized to cause retinal or occipital vasospasm.
  • Visual symptoms resolved in all patients, with one requiring hyperbaric oxygen therapy.

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Implications:

  • Clinicians should inquire about licorice ingestion in patients presenting with unexplained visual symptoms.
  • This highlights a novel association between licorice consumption and visual disturbances.
  • Understanding this link can aid in diagnosis and management of visual aberrations.