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Updated: Jul 16, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Macrolide antibiotics

R C Gordon1

  • 1Department of Pediatrics, College of Human Medicine, Michigan State University, USA.

Indian Journal of Pediatrics
|April 20, 2000
PubMed

Insights

This review covers macrolide antibiotics, detailing their spectrum, use in pediatrics, and potential drug interactions. Careful patient selection and monitoring for side effects are crucial for safe and effective macrolide antibiotic therapy.

Area of Science:

  • Pharmacology
  • Microbiology
  • Clinical Medicine

Background:

  • Macrolide antibiotics are a vital class of antimicrobials.
  • Their broad applications necessitate a comprehensive understanding of their properties.

Purpose of the Study:

  • To provide an extensive review of macrolide antibiotics.
  • To cover their antimicrobial spectrum, pharmacology, and clinical applications.

Main Methods:

  • Literature review of current information on macrolide antibiotics.
  • Synthesis of data on pharmacology, spectrum, side effects, and pediatric use.

Main Results:

  • Macrolides exhibit a defined antimicrobial spectrum.
  • Key pharmacological properties, common complications, and side effects are detailed.
  • Specific considerations for pediatric use are highlighted.

Conclusions:

  • Macrolide antibiotics require careful patient selection for optimal outcomes.
  • Physicians must remain vigilant for potential drug-drug interactions with macrolides.

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