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Published on: November 3, 2014
Indian red scorpion envenoming
1Bawaskar Hospital and Research Centre, Mahad Raigad, Maharashtra.
Insights
Early prazosin treatment significantly reduces scorpion sting complications in children. Prompt medical attention for scorpion envenoming is crucial to improve outcomes and prevent severe morbidity and mortality.
Area of Science:
- Pediatrics
- Toxicology
- Clinical Medicine
Background:
- Scorpion envenoming is a significant health concern in children, particularly in regions like Maharashtra, India.
- Clinical manifestations include hypertension, tachycardia, and acute pulmonary edema, with delayed treatment increasing mortality risk.
Purpose of the Study:
- To investigate the clinical course and treatment outcomes of scorpion envenoming in pediatric patients.
- To evaluate the efficacy of prazosin hydrochloride in managing scorpion sting complications.
Main Methods:
- A retrospective study of 293 children treated for scorpion envenoming at a hospital in Mahad, Maharashtra.
- Analysis of clinical symptoms, time to presentation, and outcomes following prazosin administration.
Main Results:
- Hypertension (38%), tachycardia (29.6%), and acute pulmonary edema (24.5%) were common complications.
- Delayed presentation (>24 hours) was associated with higher mortality (6%) due to multiorgan failure, loss of consciousness, and convulsions.
- Early oral administration of prazosin (125-250 ug) improved clinical symptoms.
Conclusions:
- The time between scorpion sting and prazosin administration is critical in determining morbidity and mortality.
- Prazosin hydrochloride is an effective early intervention for managing scorpion envenoming in children.
Abstract:
The clinical course and treatment outcome of scorpion envenoming in 293 children was studied in a hospital at Mahad in Raigad district of Maharastra. 111 (38%) children who reported 1-10 hours (mean 3.5 hours) after sting had hypertension, 87 (29.6%) with tachycardia reported within 1-24 hours (mean 6.7 hours) of being envenomed and 72 (24.5%) children developed acute pulmonary edema after 6-24 hours (mean 8 hours) of sting. Six victims were brought dead, while 17 (6%) died later owing to multiorgan failure with loss of consciousness and convulsions (who reported after 24 hours of sting). Early administration of prazosin (125-250 ug orally) improved the clinical symptoms. Morbidity and mortality due to scorpion envenoming depends upon time lapse between sting and administration of post synaptic alpha-1 blocker, prazosin hydrochloride.
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