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The effect of antioxidants on global and cytokine gene expression in T lymphocytes

K Hardy1, N H Hunt

  • 1Department of Pathology, University of Sydney, New South Wales, Australia.

Redox Report : Communications in Free Radical Research
|April 20, 2000
PubMed
Abstract

No abstract available in PubMed .

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
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