Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Free electron laser lithotripsy: threshold radiant exposures.

K F Chan1, D X Hammer, B Choi

  • 1Department of Electrical and Computer Engineering, The University of Texas at Austin, 78712, USA. kfchan@ccwf.cc.utexas.edu

Journal of Endourology
|April 20, 2000
PubMed
Summary

The study found that lower optical absorption in urinary calculi requires higher radiant exposures for ablation. High absorption significantly reduces the energy needed for fragmentation, improving lithotripsy efficiency.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Redesigning healthcare: an interview with Dr Fei-chau Pang.

Hong Kong medical journal = Xianggang yi xue za zhi·2024
Same author

Outcomes after right-sided colon surgery in Crohn's disease versus cancer.

Techniques in coloproctology·2024
Same author

Ancient and modern DNA track temporal and spatial population dynamics in the European fallow deer since the Eemian interglacial.

Scientific reports·2024
Same author

The use of botulinum toxin in the acute management of symptomatic complex incisional hernia: a case series.

Hernia : the journal of hernias and abdominal wall surgery·2023
Same author

Disposable versus reusable fibre-optic nasendoscopes: a national survey of UK ENT surgical trainees and a single-centre cost-analysis.

The Journal of laryngology and otology·2022
Same author

Simulation-based teaching: an effective modality for providing UK foundation doctors with core ENT skills training.

The Journal of laryngology and otology·2022

Area of Science:

  • Biophysics
  • Materials Science
  • Urology

Background:

  • Urinary calculi (kidney stones) pose a significant health challenge.
  • Effective fragmentation of calculi is crucial for successful lithotripsy.
  • Understanding the interaction of laser wavelengths with calculi composition is key to optimizing treatment.

Purpose of the Study:

  • To establish the threshold radiant exposures for infrared laser ablation of various urinary calculi.
  • To investigate the relationship between these thresholds, infrared wavelengths, and optical absorption coefficients.
  • To determine the correlation between ablation thresholds and lithotripsy efficiency.

Main Methods:

  • Human calculi (uric acid, calcium oxalate monohydrate, cystine, magnesium ammonium phosphate hexahydrate) were irradiated.

Related Experiment Videos

  • A free electron laser (FEL) was used at six infrared wavelengths (2.12–6.45 µm).
  • Threshold radiant exposures were measured as a function of wavelength and calculus type.

    • Main Results:

    • Threshold radiant exposures increased with decreased optical absorption.
    • Thresholds exceeded 1.5 J/cm² at low-absorption near-infrared wavelengths.
    • Thresholds dropped below 0.5 J/cm² in high-absorption regions for all calculus types.
    • Differences in thresholds between high- and low-absorption regions were statistically significant (P < 0.05).

    Conclusions:

    • Optical absorption coefficients predict lithotripsy efficiency.
    • Lower ablation thresholds require less radiant exposure for material breakdown.
    • Reduced energy for breakdown leads to increased fragmentation and higher lithotripsy efficiency.