Color-coding reveals tandem repeats in the Escherichia coli genome
1Graduate School of Mathematics, Nagoya University, Nagoya, Chikusa-ku, 464-8602, Japan.
Journal of Molecular Biology
|April 25, 2000
Abstract:
Genomic DNA contains a wide variety of repetitive sequences. In Escherichia coli, there have been several classes of repetitive sequences reported, some of which cluster as tandem repeats. We propose a novel method for analyzing symbolic sequences by two-dimensional pattern formation with color-coding. We applied this method for searching tandem repeats in the E. coli genome and found approximately 50 repeats with periods longer than 30 bases. The longest repeat has a period of 1267 bases.
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