Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pyogenic arthritis in adults.

J J Dubost1, M Soubrier, B Sauvezie

  • 1Rheumatology Department, Gabriel Montpied Hospital, Clermont-Ferrand, France.

Joint Bone Spine
|April 25, 2000
PubMed
Summary

Septic arthritis remains a significant health concern, causing lasting disability and high mortality, especially in vulnerable patients. Early diagnosis via joint aspiration and prompt antibiotic treatment are crucial for managing this serious joint infection.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Algorithms to identify chronic inflammatory rheumatism and psoriasis in medico-administrative databases: A review of the literature].

Revue d'epidemiologie et de sante publique·2021
Same author

Disease-modifying drug retention rate according to patient age in patients with early rheumatoid arthritis: analysis of the ESPOIR cohort.

Rheumatology international·2021
Same author

A six-week antibiotic treatment of endocarditis with spondylodiscitis is not associated with increased risk of relapse: A retrospective cohort study.

Infectious diseases now·2020
Same author

Cannabis use assessment and its impact on pain in rheumatologic diseases: a systematic review and meta-analysis.

Rheumatology (Oxford, England)·2020
Same author

Agranulocytosis under biotherapy in rheumatoid arthritis: three cases hypothesis of parvovirus B19 involvement in agranulocytosis observed under tocilizumab and rituximab for the treatment of rheumatoid arthritis.

Clinical rheumatology·2016
Same author

French validation of the Foot Function Index (FFI).

Annals of physical and rehabilitation medicine·2015

Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Rheumatology

Background:

  • Septic arthritis incidence is unchanged, posing risks of functional impairment and mortality, particularly in debilitated individuals.
  • Key risk factors include advanced age, diabetes, rheumatoid arthritis, immunodeficiency, and pre-existing joint conditions.
  • Staphylococcus aureus is the predominant pathogen, followed by streptococci and gram-negative bacilli, with the knee being the most common site.

Purpose of the Study:

  • To review the current understanding of septic arthritis, including its epidemiology, risk factors, causative organisms, and common sites.
  • To emphasize diagnostic strategies, focusing on joint aspiration and timely antibiotic administration.
  • To discuss the emerging challenge of prosthetic joint infections and the potential role of anti-inflammatory therapies.

Main Methods:

  • Review of existing literature on septic arthritis epidemiology, risk factors, microbiology, and clinical presentation.
  • Emphasis on diagnostic procedures, including joint aspiration techniques (ultrasound-guided if necessary) and immediate antibiotic initiation.
  • Discussion of management strategies, including arthroscopic drainage and differentiation between acute and chronic prosthetic joint infections.

Main Results:

  • Septic arthritis continues to cause significant morbidity and mortality despite advances in antimicrobial therapy.
  • Polyarticular involvement occurs in over 10% of cases, often associated with bacteremia and rheumatoid arthritis.
  • Prosthetic joint infections are increasingly prevalent, requiring careful distinction between acute and chronic forms for appropriate management.

Conclusions:

  • Prompt diagnosis through joint aspiration and immediate antibiotic treatment are critical for managing septic arthritis.
  • Distinguishing prosthetic joint infections is essential for successful treatment and prosthesis salvage.
  • Further research is needed to establish the efficacy and safety of early anti-inflammatory therapies in limiting joint damage.

Related Experiment Videos