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Cloning and sequence analysis of cDNA for diuretic hormone receptor from the Bombyx mori
1Faculty of Food Science and Biotechnology, Pukyong National University, Pusan, Korea.
Molecules and Cells
|April 25, 2000
Abstract:
The insect diuretic hormone (DH) binds to their receptor in malpighian tubules, and stimulates water secretion and cAMP synthesis. Complementary DNA encoding a diuretic hormone receptor was cloned from the malpighian tubules of Bombyx mori. The cloned cDNA encodes a protein consisting of 391 amino acid residues with the seven transmembrane domains. The receptor protein is homologous with that of other insects, and is structurally related to G-protein coupled receptors such as corticotropin relating factor (CRF), secretin, and vasoactive intestinal peptide.