Related Experiment Video
Updated: Jul 7, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
Sleep attacks and Parkinson's disease treatment
Dopamine agonist medications, including bromocriptine, lisuride, pergolide, and piribedil, may cause sudden sleep attacks in Parkinson's disease patients. This risk highlights the importance of monitoring for excessive daytime sleepiness during treatment.
Area of Science:
- Neurology
- Pharmacology
Background:
- Parkinson's disease is a neurodegenerative disorder affecting motor control.
- Dopamine agonists are commonly prescribed to manage Parkinson's symptoms.
Observation:
- Three Parkinson's disease patients experienced "sleep attacks" while driving.
- These events occurred during treatment with bromocriptine, lisuride, pergolide, or piribedil.
Findings:
- The observed sleep attacks suggest a potential link between dopamine agonists and sudden-onset sleepiness.
- All tested dopamine agonists (bromocriptine, lisuride, pergolide, piribedil) are implicated.
Implications:
- Healthcare providers should be aware of this potential side effect.
- Patients on dopamine agonists should be monitored for excessive daytime sleepiness and advised about driving safety.
More Related Videos
05:34Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders
Published on: August 18, 2023
04:53Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Published on: October 18, 2024
Related Concept Videos
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Management of Insomnia
Sedatives and Hypnotics Drugs: Miscellaneous Agents
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Sleepwalking and Sleep Talking
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
REM Sleep Behavior Disorder
RBD is significantly associated with...
Narcolepsy