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White blood cells 1: non-malignant disorders

W Stock1, R Hoffman

  • 1Department of Medicine, University of Illinois at Chicago School of Medicine, USA.

Lancet (London, England)
|April 25, 2000
PubMed

Disorders of white cells are very common in clinical practice. White-cell development and numbers are controlled by a mixture of external stimuli including cytokines, matrix proteins, and accessory cells. Several different white-cell lineages are recognised; each has a role in host defence. Both white-cell deficiency and overproduction can lead to disease. Some forms of inherited white-cell deficiency are potentially treatable with gene therapy.

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