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Patterns of infant mortality caused by major congenital anomalies
1Bureau of Reproductive and Child Health, Laboratory Centre for Disease Control, Ottawa, Canada. shi_wu_wen@hc-sc.gc.ca
Insights
Infant mortality from congenital anomalies has significantly decreased in Canada due to improved perinatal care. However, the reduction in infant deaths varied across different types of congenital anomalies.
Area of Science:
- Perinatal care research
- Public health
- Pediatric mortality studies
Background:
- Investigated the influence of advancements in perinatal care on infant mortality rates attributed to congenital anomalies.
- Examined trends in infant deaths caused by major congenital anomalies.
Purpose of the Study:
- To assess the impact of recent improvements in perinatal care on infant mortality linked to congenital anomalies.
- To analyze trends in congenital anomaly-related infant mortality in Canada.
Main Methods:
- Utilized Statistics Canada's birth and death records from 1981-1995.
- Analyzed data from 2,878,826 live births, 21,883 infant deaths, and 6,908 deaths due to congenital anomalies.
Main Results:
- Infant mortality due to major congenital anomalies declined from 3.11 to 1.89 per 1,000 live births between 1981 and 1995.
- Significant reductions were observed in mortality rates for specific anomalies, including cardiovascular and digestive system anomalies.
Conclusions:
- Recent Canadian data indicate a substantial decrease in infant deaths from major congenital anomalies.
- The extent of reduction in infant mortality varied significantly among different types of congenital anomalies.
Background:
We assessed the impact of recent advances in perinatal care on infant mortality due to congenital anomaly.
Methods:
Analysis of trends in congenital anomaly-attributed infant mortality, using the 1981-1995 Statistics Canada's birth and death records, with a total of 2,878,826 live births, 21,883 infant deaths, and 6, 908 infant deaths due to congenital anomalies.
Results:
Infant mortality due to major congenital anomaly decreased from 3.11 per 1, 000 live births in 1981 to 1.89 per 1,000 live births in 1995. Cause-specific infant mortality rates for anencephaly, spina bifida, other central nervous system anomalies, cardiovascular system anomalies, respiratory system anomalies, digestive system anomalies, certain musculoskeleton anomalies, urinary system anomalies, chromosomal anomalies, and multiple congenital anomalies were 0.20, 0.23, 0.27, 1.04, 0.24, 0.08, 0.22, 0.16, 0.22, and 0.13 per 1,000 live births, respectively, in 1981-1983, whereas corresponding rates were 0.07, 0.07, 0.18, 0.73, 0.25, 0.03, 0.12, 0.12, 0.26, and 0.06 per 1,000 live births, respectively, in 1993-1995.
Conclusions:
Recent Canadian data show that infant deaths caused by major congenital anomalies have decreased significantly, but reductions varied substantially according to specific forms of anomalies.