Relationship between breast milk feeding and atopic dermatitis in children
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Published on: September 26, 2019
Y Nakamura1, I Oki, S Tanihara
1Department of Health Science, Jichi Medical School, Tochigi, Japan.
Insights
Breast milk feeding slightly increases the risk of atopic dermatitis in children, though not significantly. Later parity orders may also elevate this risk, warranting further investigation into infant nutrition and eczema development.
Area of Science:
- Pediatrics
- Dermatology
- Epidemiology
Background:
- Atopic dermatitis is a common childhood condition with complex etiology.
- The role of infant feeding practices, particularly breastfeeding, in atopic dermatitis development remains a subject of research.
Purpose of the Study:
- To investigate the association between breast milk feeding and the prevalence of atopic dermatitis in 3-year-old children.
- To identify potential risk factors for atopic dermatitis in early childhood.
Main Methods:
- A cross-sectional study involving 3856 children aged 3 years.
- Data collected via questionnaires on infant nutrition, maternal factors, and atopic dermatitis history.
- Unconditional logistic regression models used for adjusted analyses.
Main Results:
- Breast milk feeding showed a slightly elevated, but not statistically significant, risk of atopic dermatitis (OR = 1.16, 95% CI 0.96-1.40).
- Maternal age over 30 and second or later parity orders also showed non-significant increases in risk.
- No statistically significant associations were found after adjusting for confounding factors.
Conclusions:
- Breast milk feeding may be associated with a minor, non-significant increase in atopic dermatitis risk.
- The risk might be influenced by parity order, suggesting a potential interaction.
- Further research is needed to elucidate the complex relationship between infant feeding and atopic dermatitis.
Objective:
To determine whether or not the breast milk feeding has a role in the prevalence of atopic dermatitis among children.
Methods:
The target population of the study was all children participating in health check-up program for 3-year-old children in 60 municipalities locating 10 selected prefectures during designated 2 months between October and December 1997. Using a questionnaire, information on nutrition in infants (breast milk only, bottled milk only, or mixed), parity, mothers' age at birth, and a history of atopic dermatitis was obtained. Besides, data on potential confounding factors were obtained.
Results:
Questionnaires from 3856 children (81.6% of those who were to participate in the programs, and 96.4% of children who participated them) were analyzed. After the adjustment for all potential confounding factors using unconditional logistic models, the risk of atopic dermatitis was slightly higher among children with breast milk (odds ratio [OR] = 1.16 with 95% confidence interval [CI] 0.96-1.40). Mothers' age at birth (OR for those who were more than 30 years or older in comparison with those who were younger than 30 years = 1.15; 95% CI, 0.96-1.37) and those with second or later parity orders (OR = 1.14, 95% CI; 0.95-1.35) showed odds ratios that were higher than unity without statistical significance.
Conclusion:
Breast milk elevates the risk of atopic dermatitis slightly without statistical significance; the risk may be, however, higher in children in second or later parity orders.
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