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Related Experiment Videos

Detailed colonoscopy for detecting early superficial carcinoma: recent developments.

S Tanaka1, K Haruma, M Ito

  • 1Department of Endoscopy, Hiroshima University Medical Hospital, Japan.

Journal of Gastroenterology
|April 25, 2000
PubMed
Summary

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Superficial colorectal cancer (CRC) is often found during colonoscopies. Magnifying colonoscopy

Area of Science:

  • Gastroenterology
  • Oncology
  • Endoscopy

Background:

  • Routine colonoscopic examinations frequently detect early superficial colorectal carcinoma (CRC).
  • A significant proportion of early CRCs are macroscopically superficial.
  • Depressed-type colorectal lesions exhibit higher malignant potential than elevated types.

Purpose of the Study:

  • To evaluate the utility of pit pattern classification using magnifying video-colonoscopy for diagnosing early colorectal cancer.
  • To correlate pit patterns with histological findings and invasion depth in colorectal neoplasias.
  • To assess the malignant potential of depressed versus elevated colorectal lesions.

Main Methods:

  • Analysis of 769 early CRCs and 4821 adenomas diagnosed via colonoscopy (1991-1998).

Related Experiment Videos

  • Magnifying video-colonoscopy observations of 265 colorectal neoplasias using Kudo's pit pattern classification.
  • Comparison of pit patterns (IIIs, V, III(L), V(N)) with lesion morphology and invasion depth.

    • Main Results:

    • Depressed-type lesions were characterized by IIIs and V pit patterns, while elevated lesions showed III(L) patterns.
    • Lesions with IIIs and V pit patterns had a significantly higher incidence of cancer.
    • The V(N) pit pattern was a significant indicator of submucosal invasion.
    • Superficial early CRC constitutes approximately one-third of all early CRCs, with depressed types showing higher malignancy.

    Conclusions:

    • Pit pattern observation via magnifying video-colonoscopy is a valuable tool for predicting histology and invasion depth in early colorectal cancer.
    • Depressed-type superficial early colorectal cancers possess a significantly higher malignant potential compared to elevated types.
    • Magnifying colonoscopy aids in differentiating between adenomas and early CRCs, guiding treatment decisions.