Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Changes in cortical bone mineralization in the developing mandible: a three-dimensional quantitative computed

K Maki1, A Miller, T Okano

  • 1Department of Orthodontics, Showa University, Tokyo, Japan.

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
|April 26, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of dopamine on T-lymphocyte proliferative responses and serum prolactin concentrations in critically ill patients.

Critical care medicine·1992
Same author

Lung function testing: selection of reference values and interpretative strategies.

The American review of respiratory disease·1992
Same author

Defense behavior and coping in an autistic savant: the story of Temple Grandin, PhD.

Psychiatry·1992
Same author

Comparative quantitative evaluation of pleural fibrosis and its effects on pulmonary function in two large asbestos-exposed occupational groups--insulators and sheet metal workers.

Environmental research·1992
Same author

Identification of a repetitive element in the snail Biomphalaria glabrata: relationship to the reverse transcriptase-encoding sequence in LINE-1 transposons.

Gene·1992
Same author

On creativity.

Arthritis and rheumatism·1992

Quantitative computed tomography (QCT) reveals significant differences in mandibular bone mineral density (BMD) development between males and females. Males show accelerated cortical bone maturation and a higher ratio of cortical to total bone after age 11.

Area of Science:

  • Biomedical Engineering
  • Radiology
  • Anthropology

Background:

  • Mandibular bone development and mineralization are crucial for facial structure and function.
  • Understanding age- and sex-related changes in mandibular bone mineral density (BMD) is important for growth assessment and clinical applications.

Purpose of the Study:

  • To investigate the three-dimensional distribution of cortical bone mineral density (BMD) in the mandible across different age groups and sexes.
  • To identify developmental patterns and potential sexual dimorphism in mandibular mineralization.

Main Methods:

  • Quantitative computed tomography (QCT) was performed on 34 subjects aged 9–33 years with symmetrical mandibles.
  • Pixel analysis determined BMD distribution at three levels: entire mandible, cortical bone (60% segmentation), and highest mineralized cortical bone (>1250 mg/cm³).

Related Experiment Videos

  • Three-dimensional reconstructions visualized the geometrical distribution of highly mineralized areas.

    • Main Results:

    • Total mandibular bone volume increased significantly with age across all subjects.
    • After age 11, males exhibited a significantly larger total mandibular bone volume compared to females.
    • Cortical bone and highest mineralized bone content increased significantly with maturation, particularly between ages 13 and 16.
    • The ratio of cortical bone to total bone increased more rapidly in males, plateauing by age 16, indicating sex-specific mineralization patterns.

    Conclusions:

    • Mandibular bone mineral density distribution shows significant developmental changes throughout adolescence and into early adulthood.
    • Distinct sex-based differences in mandibular bone maturation and mineralization emerge after age 11, with males demonstrating accelerated cortical bone development.
    • These findings highlight the importance of considering age and sex when evaluating mandibular bone structure and density.