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Haptoglobin 1F allele frequency is high among indigenous populations in the state of Durango, Mexico
J Delanghe1, M Langlois, C Alvarado Esquivel
1Department of Clinical Chemistry, University Hospital, Gent, Belgium. joris.delanghe@rug.ac.be
Human Heredity
|April 27, 2000
Abstract:
We studied haptoglobin polymorphism in Mexican populations with high Indian ancestry living in isolated and urban areas in the state of Durango. Analysis with respect to the HP*1F and HP*1S allelic subtypes by isoelectric focusing showed unusually high HP*1F allele frequencies among urban (0.370) and isolated Mexican Indians (0.383). Comparison with other population studies demonstrated a geographical cline of the HP*1F allele increasing in the same direction of the HP*1 allele, while HP*1S frequency does not show racial differences.