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Suitably functionalised pyrimidines as potential antimycotic agents
N Agarwal1, S K Raghuwanshi, D N Upadhyay
1Division of Medicinal Chemistry, Central Drug Research Institute, Lucknow, India.
Bioorganic & Medicinal Chemistry Letters
|April 27, 2000
Abstract:
Various suitably functionalized pyrimidine derivatives have been synthesized to explore their potential as antimycotic agents. Some of the synthesized compounds 4c, 4d, 8a-e have shown highly significant in vitro antifungal activity against five human pathogenic fungi.