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Related Experiment Videos

The FAA's postmortem forensic toxicology self-evaluated proficiency test program: the first seven years.

A K Chaturvedi1

  • 1Toxicology and Accident Research Laboratory, Aeromedical Research Division, Civil Aeromedical Institute, Federal Aviation Administration, US Department of Transportation, Oklahoma City, OK 73125-5066, USA.

Journal of Forensic Sciences
|April 27, 2000
PubMed
Summary

Proficiency testing in forensic toxicology now includes decomposed samples and solid tissues. This quality assurance program enhances laboratory performance and supports accreditation for forensic toxicology services.

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Area of Science:

  • Forensic Toxicology
  • Analytical Chemistry
  • Quality Assurance

Background:

  • Existing proficiency testing (PT) programs lack the complexity required for postmortem forensic toxicology.
  • Current PT programs do not incorporate challenging samples like decomposed biological materials and solid tissues.

Purpose of the Study:

  • To establish a proficiency testing program addressing the unique challenges of postmortem forensic toxicology.
  • To facilitate voluntary, interlaboratory, and self-evaluation for professional development and technical currency.
  • To quantitatively assess analytical methods in the presence and absence of interfering substances.

Main Methods:

  • The Federal Aviation Administration initiated a PT program in July 1991.
  • Quarterly distribution of PT samples (blood, plasma, urine, kidney, liver) with and without drugs, metabolites, and chemicals.

Related Experiment Videos

  • Analysis of 28 diverse PT samples by approximately 30 participating laboratories representing various institutions.
  • Anonymized results summaries provided to participants for self-evaluation.

    • Main Results:

    • Analytical findings were generally consistent with expected values, though dependent on sample condition and analytes.
    • Some concerning incidences of false positives were observed.
    • The program provides a valuable tool for quality assurance and quality control in forensic toxicology.

    Conclusions:

    • The established PT program effectively addresses the complexities of postmortem forensic toxicology.
    • Participation in this program supports laboratory accreditation by the American Board of Forensic Toxicology.
    • The program is crucial for enhancing the quality and reliability of forensic toxicology services.