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Malignant melanoma arising in a choroidal magnacellular nevus (melanocytoma)
A E Barker-Griffith1, P R McDonald, W R Green
1Eye Pathology Laboratory, Wilmer Institute, Philadelphia, Pennsylvania.
Abstract:
A case is presented of a 55-year-old Caucasian male whose right eye was enucleated for a mixed spindle-A and spindle-B malignant melanoma in 1967. The ophthalmoscopic picture, fluorescein angiography, and overlying peculiar orange pigmentation were suggestive of a malignant lesion. Study of serial sections of the entire lesion made possible the histologic reconstruction of the lesion, clinicopathologic correlation of the yellow-orange pigment, and the location of the nevus and mixed spindle-cell melanoma components.