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Related Experiment Videos

Attenuated cardiovascular adjustment to sustained static exercise after carbohydrate loading.

T Sadamoto1, M Kusano, T Yamagiwa

  • 1Graduate School of Human Culture, Nara's Women's University, Division of Integrated Sciences, Japan. sadamoto@cc.nara-wu.ac.jp

Journal of the Autonomic Nervous System
|April 28, 2000
PubMed
Summary

Carbohydrate loading increased lactic acid but did not enhance the exercise metaboreflex. Cardiovascular responses to exercise were attenuated, suggesting other mechanisms beyond lactic acid influenced these changes.

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Area of Science:

  • Exercise Physiology
  • Metabolic Regulation
  • Cardiovascular Response

Background:

  • Carbohydrate loading is known to increase plasma lactic acid (LA) levels.
  • The metaboreflex, activated by LA, influences cardiovascular responses during exercise.
  • The specific impact of CHO-loading-induced LA on the metaboreflex and exercise hemodynamics requires clarification.

Purpose of the Study:

  • To investigate if elevated plasma LA from carbohydrate (CHO)-loading potentiates the LA-induced metaboreflex.
  • To determine the effect of CHO-loading on cardiovascular and neuromuscular responses during sustained static exercise.
  • To elucidate the relationship between LA concentration, cardiovascular adjustments, and perceived exertion post-CHO-loading.

Main Methods:

  • 16 volunteers underwent a CHO-loading protocol including exhaustive exercise and specific dietary phases.

Related Experiment Videos

  • Measurements included plasma LA, mean arterial blood pressure (MAP), heart rate (HR), cardiac output (CO), rating perceived exertion (RPE), and vastus lateralis iEMG.
  • These variables were assessed during sustained static knee extension before and after CHO-loading.

    • Main Results:

    • CHO-loading significantly increased LA concentration in the exercising leg.
    • Despite increased LA, MAP, HR, and CO responses during exercise were significantly attenuated post-CHO-loading.
    • A significant reduction in RPE and iEMG was observed in the exercising leg after CHO-loading.

    Conclusions:

    • Increased plasma LA concentration from CHO-loading did not enhance the LA-induced metaboreflex during sustained static exercise.
    • Attenuated cardiovascular responses post-CHO-loading appear to be mediated by mechanisms other than increased LA, potentially involving reduced RPE and iEMG.
    • The findings suggest a dissociation between elevated LA and the metaboreflex-mediated cardiovascular control during exercise following CHO-loading.