Haliclonyne, a new highly oxygenated polyacetylene from the marine sponge Haliclona species

Haliclonyne (1), a new polyacetylene carboxylic acid, has been isolated from the marine sponge Haliclona sp. collected in the Gulf of Eilat. The structure of haliclonyne, a C(47) oxo-octahydroxy-dienetetrayne carboxylic acid, was elucidated by interpretation of NMR and mass spectra of 1 and two of its derivatives.