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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Intracoronary Stenting for Restenosis: Long-Term Follow-up: A Single Center Experience
1Division de Cardiologie, Centre Hospitalier Universitaire Vaudois, Rue du Bugnon, 1011, Lausanne, Switzerland.
The Journal of Invasive Cardiology
|July 1, 1996
Summary
Coronary artery stenting effectively treats restenosis after angioplasty in native arteries and venous grafts. This strategy shows good long-term outcomes, with high event-free survival and survival rates.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Biomedical Engineering
Background:
- Restenosis following angioplasty is a significant clinical challenge.
- Coronary artery stenting has emerged as a treatment option for restenosis.
- Evaluating the long-term efficacy and safety of coronary stenting is crucial.
Purpose of the Study:
- To assess the long-term outcomes of coronary stent implantation for treating restenosis.
- To evaluate the safety and effectiveness of stenting in native coronary arteries and venous grafts.
Main Methods:
- A cohort of 106 patients received 113 coronary stents (Wallstents, Palmaz-Schatz, Wiktor) for restenosis.
- Stents were implanted in native coronary arteries (86 cases) and venous grafts (20 cases).
- Clinical and angiographic follow-up was conducted at 6 months, and long-term follow-up extended to an estimated 104 months.
Main Results:
- Stent implantation successfully increased minimal lumen diameter in both native arteries and venous grafts.
- At 6 months, clinical events occurred in 20% of patients (including deaths, myocardial infarctions, and re-angioplasty).
- Long-term follow-up (mean 65 months) showed sustained efficacy, with 70% of patients remaining event-free and a 95% survival rate.
Conclusions:
- Coronary stent implantation is a valid and effective strategy for treating restenosis after conventional balloon angioplasty.
- The procedure demonstrates favorable long-term clinical and angiographic results.
- Stenting offers a durable solution for patients with restenosis in both native coronary arteries and venous grafts.

