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[The effect of aneurysm resection on left ventricular function].

M Schönbeck, A Senning, W Rutishauser

Deutsche Medizinische Wochenschrift (1946)

|January 17, 1975

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Successful aortocoronary bypass surgery significantly improved left ventricular (LV) function in patients with coronary-artery disease and ventricular aneurysm. Post-surgery, patients showed enhanced ejection fraction and improved ventricular wall motion.

Area of Science:

Cardiology
Cardiac Surgery
Diagnostic Imaging

Background:

Coronary artery disease (CAD) often leads to left ventricular (LV) dysfunction and aneurysm formation.
Surgical intervention, including aortocoronary bypass grafting (ACBG) and ventricular aneurysm resection, aims to restore cardiac function.
Assessing the impact of these combined surgical procedures on LV mechanics is crucial for patient outcomes.

Purpose of the Study:

To evaluate the effect of successful ACBG and ventricular aneurysm resection on LV function in patients with CAD.
To quantify changes in LV volumes, ejection fraction, and regional wall motion post-surgery.

Main Methods:

Retrospective analysis of 13 patients with CAD and ventricular aneurysm undergoing ACBG and aneurysmectomy.
Left ventricular cine-angiography (single-plane, right anterior oblique) performed pre- and post-operatively.

Related Experiment Videos

Calculation of LV end-diastolic volume index (EDVI), end-systolic volume index (ESVI), stroke volume index (SVI), ejection fraction (EF), and regional wall motion parameters (SMV, SMH, SMS).

Main Results:

Significant improvements observed 11 months post-surgery compared to baseline (4 months pre-op).
Mean EF increased from 32.6% to 54.6%.
Significant improvements in LV end-diastolic volume index (154 to 126 ml/m2), end-systolic volume index (107 to 56 ml/m2), and stroke volume index (46.5 to 69.9 ml/m2).
Marked enhancement in anterior wall motion (SMV: 6.1% to 25.0%) and apical motion (SMS: 5.1% to 13.1%).

Conclusions:

Aortocoronary bypass surgery combined with ventricular aneurysm resection leads to substantial improvement in left ventricular function.
The surgical approach effectively enhances global and regional ventricular contractility in patients with severe cardiac failure due to CAD and aneurysm.