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Superficial microcystic corneal dystrophy.

M N Luxenberg, B R Friedland, J M Holder

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |February 1, 1975
    PubMed
    Summary
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    Microcystic corneal dystrophy presents subtle changes, often missed in routine exams. This study found no link between tear function and the condition, noting it appears benign with minimal symptoms.

    Area of Science:

    • Ophthalmology
    • Corneal Diseases
    • Human Pathology

    Background:

    • Microcystic corneal dystrophy (MCCD) was first described in 1964.
    • Subsequent reports have detailed associated corneal changes, but the etiology remains unknown.
    • Pathological studies exist, yet MCCD's subtle signs can be overlooked during standard eye examinations.

    Purpose of the Study:

    • To further evaluate the clinical signs and symptoms of microcystic corneal dystrophy.
    • To emphasize effective examination techniques for diagnosing MCCD.
    • To investigate potential associations between tear function and MCCD.

    Main Methods:

    • Study included 17 patients diagnosed with microcystic corneal dystrophy.
    • Comprehensive clinical evaluations were performed.

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  • Detailed laboratory assessments of tear function were conducted.

    • Main Results:

    • No definitive association was found between tear function parameters and the observed corneal changes.
    • The corneal abnormalities in this patient cohort were characterized as subtle.
    • Patients reported minimal symptoms, suggesting a benign clinical course.

    Conclusions:

    • Microcystic corneal dystrophy appears to be a benign condition with minimal symptomatology in the studied group.
    • Tear function does not seem to be a significant factor in the development or presentation of MCCD.
    • Further research into examination techniques may aid in earlier detection of subtle corneal changes.