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Updated: Oct 16, 2026

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
Published on: March 24, 2015
[Use of interferon-alpha (IFN-alpha) in the treatment of keratoacanthoma]
1Semmelweis Medizinische Universität, Klinik für Haut- und Geschlechtskrankheiten, Budapest, Ungarn.
Background And Objective:
Keratoacanthoma are benign epithelial tumors. The aim of this study was to determine the effects of interferon alpha on keratoacanthoma.
Patients/Methods:
Six patients presented with histologically proven keratoacanthoma which were large or otherwise difficult to excise. Intra and perilesional interferon-alpha treatment with 3 million IU weekly was started.
Results:
In 6-15 weeks all tumors were cured.
Conclusions:
Treatment with intralesional interferon-alpha offers a new possibility in cases of large keratoacanthomas, or those which are not surgically excisable.
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