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[Dynamic MR mammography. Multidimensional visualization of contrast medium enhancement in virtual reality]
K H Englmeier1, J Griebel, R Lucht
1GSF-Forschungszentrum für Umwelt und Gesundheit, Institut für Medizinische Informatik und Systemforschung, Neuherberg. englmeier@gsf.de
Background:
The purpose of this study was the development of a method for fast and efficient analysis of dynamic MR images of the female breast. The image data sets were acquired with a saturation-recovery turbo-FLASH sequence which enables the detection of the kinetics of the contrast agent concentration in the whole breast with a high temporal and spatial resolution. In addition, a morphologic 3D-FLASH data set was acquired.
Methods:
The dynamic image datasets were analyzed by a pharmacokinetic model which enables the representation of the relevant functional tissue information by two parameters. In order to display simultaneously morphologic and functional tissue information, we developed a multidimensional visualization system, which enables a practical and intuitive human-computer interface in virtual reality.
Discussions:
The developed system allows the fast and efficient analysis of dynamic MR data sets. An important clinical application is the localization and definition of multiple lesions of the female breast.