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Radical excision of multifocal anal intraepithelial neoplasia: report of a case
D J Browse1, R J Baigrie, P A Goldberg
1Department of Surgery, Groote Schuur Hospital and the University of Cape Town, South Africa.
Purpose:
The aim of this study was to describe the technique of radical excision of multifocal anal intraepithelial neoplasia and discuss controversial issues surrounding the management of this condition.
Method:
We describe the case of a 31-year-old female with previous vulval warts, vulval squamous carcinoma, and recent immunosuppression who had widespread anal intraepithelial neoplasia excised, and the resulting defect was split-skin grafted, including the anal canal.
Results:
Excision and split-skin grafting was successful in removing the disease and left a satisfactory cosmetic and functional result.
Conclusion:
Diffuse, high-grade, anal intraepithelial neoplasia is rare. Excision of these lesions remains controversial but may be the best option.
