Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Transpupillary thermotherapy.

M Ip¹, A Kroll, E Reichel

¹New England Eye Center, Boston, MA 02116, USA.

Seminars in Ophthalmology

|May 3, 2000

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Across time and space: phylogenetic analysis of carbapenem-resistant Acinetobacter baumannii in a network of general and convalescent hospitals.

The Journal of hospital infection·2025

Same author

Limb presentations of invasive Group A Streptococci infection in children.

JPRAS open·2024

Same author

Towards a better consideration of endocrine disruption within the technical guidance for deriving environmental quality standards.

Regulatory toxicology and pharmacology : RTP·2023

Same author

Risk of hospitalised bronchiectasis exacerbation based on blood eosinophil counts.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2023

Same author

Antibiotic use for respiratory tract infections among older adults living in long-term care facilities: a systematic review and meta-analysis.

The Journal of hospital infection·2022

Same author

New amidinate complexes of indium(iii): promising CVD precursors for transparent and conductive In<sub>2</sub>O<sub>3</sub> thin films.

Dalton transactions (Cambridge, England : 2003)·2017

Same journal

Maternal Diabetes Mellitus During Pregnancy as a Risk Factor for Congenital Nasolacrimal Duct Obstruction in the Offspring - a Large-Scale National Study.

Seminars in ophthalmology·2026

Same journal

Clinical Spectrum and Genetics of Ocular Manifestations in Muscle Eye Brain Disease: A Literature Review.

Seminars in ophthalmology·2026

Same journal

Port Delivery System Vs Monthly Ranibizumab in VEGF-Driven Macular Disease: A Systematic Review and Meta-Analysis.

Seminars in ophthalmology·2026

Same journal

Genome Wide Pleiotropic Analysis Reveals Shared Genetic Architecture and Pathological Basis Between Retinitis Pigmentosa and Relevant Ocular Comorbidities.

Seminars in ophthalmology·2026

Same journal

Does QuantiFERON-Positive Tubercular Serpiginous-Like Choroiditis Affect Retinal and Choroidal Structures Differently in Affected Eyes Compared to Fellow Eyes and Healthy Controls? A Comparative OCT and OCT-A Study.

Seminars in ophthalmology·2026

Same journal

Treatment Approaches for Posterior Uveitis in Ocular Sarcoidosis: A Narrative Review.

Seminars in ophthalmology·2026

See all related articles

Hyperthermia shows promise for treating eye cancers and age-related macular degeneration. Novel transpupillary thermotherapy delivers targeted heat energy to the posterior eye segment for these conditions.

Area of Science:

Ophthalmology
Oncology
Biomedical Engineering

Background:

Hyperthermia is a recognized cancer treatment modality.
Recent technological advancements enable targeted hyperthermic treatment of ocular structures.
Transpupillary thermotherapy (TTT) is a novel technique for applying hyperthermic energy to the posterior segment of the eye.

Purpose of the Study:

To review the application of transpupillary thermotherapy for posterior segment ocular diseases.
To discuss the potential of hyperthermia in treating choroidal melanoma.
To evaluate transpupillary thermotherapy for choroidal neovascularization associated with age-related macular degeneration.

Main Methods:

Review of existing literature on transpupillary thermotherapy.

Related Experiment Videos

Analysis of hyperthermia delivery methods (ultrasound, microwave, ferromagnetic energy) to ocular structures.

Focus on transpupillary thermotherapy for posterior segment diseases.

Main Results:

Transpupillary thermotherapy allows direct application of hyperthermic energy to posterior ocular structures.
The technique is being explored for treating choroidal melanoma.
Its application in age-related macular degeneration with choroidal neovascularization is under review.

Conclusions:

Transpupillary thermotherapy represents a significant advancement in delivering localized hyperthermia to the posterior eye.
Further research is warranted to establish the efficacy and safety of TTT for specific posterior segment ocular conditions like choroidal melanoma and AMD-related neovascularization.