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Published on: August 7, 2017
The risk of sinusitis in children with allergic rhinitis
1Department of Pediatrics, University of Florida College of Medicine, Gainesville 32610, USA.
Children with perennial allergic rhinitis (PAR) have a higher risk of developing bacterial sinusitis compared to those with seasonal allergic rhinitis (SAR). Mold allergy significantly increases this risk, suggesting targeted management can reduce sinusitis incidence.
Area of Science:
- Pediatric Allergy and Immunology
- Otolaryngology
- Infectious Diseases
Background:
- Bacterial sinusitis is frequently observed in individuals with allergic rhinitis, though the precise correlation remains under investigation.
- Allergic rhinitis, encompassing perennial allergic rhinitis (PAR) and seasonal allergic rhinitis (SAR), affects a significant pediatric population.
- Understanding the interplay between allergic rhinitis subtypes and sinusitis prevalence is crucial for effective clinical management.
Purpose of the Study:
- To investigate the correlation between perennial allergic rhinitis (PAR) and seasonal allergic rhinitis (SAR) and the prevalence of bacterial sinusitis in children.
- To determine if factors such as age, season, and specific allergen sensitivities influence the risk of sinusitis in children with allergic rhinitis.
Main Methods:
- A longitudinal study was conducted over five years involving 413 children diagnosed with allergic rhinitis.
- Children were categorized into two groups: 215 with PAR and 198 with SAR.
- Prevalence of sinusitis was compared between PAR and SAR groups, analyzing the impact of age, season, and airborne allergen sensitivity, particularly mold allergy.
Main Results:
- The prevalence of sinusitis was significantly higher in children with PAR compared to those with SAR, irrespective of age or season.
- Children with PAR and a mold allergy exhibited a substantially elevated risk of sinusitis (relative risk 2.49) compared to those with PAR without mold allergy (relative risk 1.50).
Conclusions:
- Perennial allergic rhinitis is a significant risk factor for developing bacterial sinusitis in children.
- Mold allergy emerges as a critical contributing factor to sinusitis development in pediatric patients with allergic rhinitis.
- Effective management strategies targeting mold allergy may play a key role in reducing the incidence of sinusitis in susceptible children.
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