Related Experiment Video
Updated: Aug 9, 2026
06:21
Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma
Published on: November 19, 2019
Strategy for pancreatic endocrine tumors
1Department of Surgery, Toyama Prefectural Central Hospital, Japan. YIB03163@niftyserve.or.jp
Hepato-Gastroenterology
|May 3, 2000
Summary
Complete resection of liver metastases from pancreatic endocrine tumors offers the best outcome. Lipiodol-transcatheter arterial embolization provides effective palliation for unresectable liver metastases.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Oncology
Background:
- Pancreatic endocrine tumors are rare with no standard therapy for liver metastases.
- Evaluating therapeutic options for liver metastases is crucial.
Purpose of the Study:
- To evaluate the efficacy of surgical resection and lipiodol-transcatheter arterial embolization for liver metastases of pancreatic endocrine tumors.
Main Methods:
- Surgical resection of primary tumors in 13 patients.
- Liver metastasis management included partial resection (2 patients) or lipiodol-transcatheter arterial embolization (2 patients).
Main Results:
- Complete resection of liver metastases correlated with long-term survival.
- Lipiodol-transcatheter arterial embolization achieved >90% tumor necrosis and normalized gastrin levels in unresectable cases.
- One patient with resected synchronous metastasis died within 5 months due to recurrence.
Conclusions:
- Complete resection of liver metastases is favorable for pancreatic endocrine tumors.
- Lipiodol-transcatheter arterial embolization is an effective palliative option for unresectable liver metastases.
- Primary tumor resection is recommended regardless of unresectable liver metastases.
