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Red cells I: inherited anaemias

D J Weatherall1, A B Provan

  • 1Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, UK.

Lancet (London, England)
|May 3, 2000
PubMed

Examination of the genetic mechanisms underlying the thalassaemias has led to a clearer understanding of the control of eukaryotic genes in general. Inherited disorders of haemoglobin synthesis are an important cause worldwide of morbidity and mortality, and place a large burden on patients, families, and ultimately communities. The haemoglobin disorders can be controlled, by counselling and prenatal diagnosis. Treatment is usually symptomatic, though bone-marrow transplantation for beta-thalassaemia may be successful in suitable patients.

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