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Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
Published on: August 9, 2012
Bladder calculi in children who perform clean intermittent catheterization
U Barroso1, R Jednak, P Fleming
1Department of Paediatric Urology, Children's Hospital of Michigan and Wayne State University School of Medicine, Detroit, Michigan, USA.
BJU International
|May 3, 2000
Summary
Clean intermittent catheterization (CIC) increases bladder stone risk, though augmentation doesn't significantly alter incidence. Mitrofanoff conduits showed a slight increase, and open cystolithotomy had lower recurrence rates for bladder calculi.
Area of Science:
- Urology
- Nephrology
- Medical Devices
Background:
- Clean intermittent catheterization (CIC) is a common procedure for bladder emptying.
- Bladder calculi (stones) are a potential complication in patients using CIC.
- The influence of bladder augmentation and catheterization method on stone formation requires further investigation.
Purpose of the Study:
- To investigate clean intermittent catheterization (CIC) as a risk factor for bladder calculi.
- To assess risk factors in patients with and without bladder augmentation.
- To evaluate management strategies for bladder calculi in CIC patients.
Main Methods:
- Retrospective review of 403 patients using CIC from 1981-1998.
- Categorization into groups based on bladder augmentation and catheterization route (urethral vs. Mitrofanoff conduit).
- Statistical comparison of bladder calculi incidence and review of treatment outcomes.
Main Results:
- Bladder calculi incidence was 5-11% across groups; no significant difference based on augmentation.
- Mitrofanoff conduit use was associated with a slightly higher calculus incidence.
- 18 patients (64%) were asymptomatic; 23 (88%) had bacteriuria. Recurrence rates were 32% post-treatment.
Conclusions:
- Patients on CIC are at risk for bladder calculi, independent of bladder augmentation.
- Mitrofanoff conduits may slightly increase calculus risk.
- Open cystolithotomy showed a trend towards lower recurrence, but further study is needed.
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