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Updated: Aug 13, 2026
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Intravascular Delivery of Biologics to the Rat Kidney
Published on: September 1, 2016
Takayasu's arteritis associated with intrarenal vessel involvement
I Munir1, R Uflacker, J Milutinovic
1Department of Medicine, Division of Nephrology, and the Department of Radiology, Division of Interventional Radiology, Medical University of South Carolina, Charleston 29425, USA.
Summary
Takayasu
Area of Science:
- Vascular inflammation and nephrology.
- Rheumatology and autoimmune diseases.
Background:
- Takayasu's arteritis (TA) is a large vessel vasculitis affecting the aorta and its branches.
- Renal involvement in TA commonly presents as renal artery stenosis, leading to hypertension and ischemic kidney disease.
Observation:
- This report details a rare case of Takayasu's arteritis.
- The case presented with unusual involvement of intrarenal arteries, not previously documented in association with TA.
Findings:
- The patient exhibited clinical and arteriographic findings consistent with Takayasu's arteritis.
- Diagnostic imaging revealed vasculitis affecting the intrarenal arteries, a novel finding for this condition.
Implications:
- This case expands the known spectrum of renal manifestations in Takayasu's arteritis.
- Highlights the importance of considering intrarenal vasculitis in TA patients with renal complications.
- Suggests further research into the pathophysiology and diagnostic criteria for TA-associated intrarenal vascular involvement.
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