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Isolation of recent variant influenza types A (H3N2) & B strains in Pune, India during 1998

B L Rao1, S S Kadam

  • 1National Institute of Virology (ICMR), Pune.

The Indian Journal of Medical Research
|May 4, 2000
PubMed

Insights

Influenza surveillance in Pune, India, identified Influenza A (H3N2) and Influenza B strains in 1998. These circulating viruses matched globally prevalent strains, including A/Sydney/05/97 and B/Harbin/07/94.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • Continuous surveillance for influenza is crucial for monitoring viral circulation and emergent strains.
  • Influenza-like illness (ILI) presents a significant public health challenge globally.
  • Understanding local influenza epidemiology aids in vaccine development and public health interventions.

Purpose of the Study:

  • To investigate influenza strains circulating in Pune, India, during 1998.
  • To identify and characterize influenza A and B viruses from patients with ILI.
  • To compare isolated strains with globally prevalent influenza variants.

Main Methods:

  • Collection of throat and nasal swabs from 456 patients with ILI.
  • Processing of specimens using Madin-Darby Canine Kidney (MDCK) cell culture.
  • Isolation and identification of influenza virus strains.

Main Results:

  • Influenza type A (H3N2) and type B strains were successfully isolated.
  • The isolated Influenza A strain was identified as similar to A/Sydney/05/97 (H3N2).
  • The isolated Influenza B strain was identified as similar to B/Harbin/07/94.

Conclusions:

  • The study identified globally relevant influenza A (H3N2) and B strains circulating in Pune, India in 1998.
  • Findings highlight the importance of ongoing influenza surveillance to detect and track viral variants.
  • This data contributes to understanding influenza epidemiology in the region and informs public health strategies.

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