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Published on: January 29, 2018
Breastfeeding in early life and bone mass in prepubertal children: a longitudinal study
1Menzies Centre for Population Health Research, Hobart, Tasmania, Australia. g.jones@utas.edu.au
Insights
Breastfeeding in early life is linked to higher bone mineral density in 8-year-old children born at term. Longer breastfeeding duration (≥3 months) showed significant benefits for bone mass, suggesting early intervention for osteoporosis prevention.
Area of Science:
- Pediatrics
- Bone Health
- Nutritional Science
Background:
- Early life nutrition significantly influences long-term health outcomes.
- Bone mass accrual during childhood is a critical determinant of skeletal health in adulthood.
- Understanding factors affecting bone development is essential for preventing osteoporosis.
Purpose of the Study:
- To investigate the association between breastfeeding and bone mineral density in prepubertal children.
- To determine if breastfeeding duration impacts bone mass in early childhood.
- To explore the relationship between breastfeeding and bone density in term vs. preterm infants.
Main Methods:
- A cohort of 330 eight-year-old children from Southern Tasmania was studied.
- Breastfeeding habits were assessed retrospectively.
- Bone mineral density was measured using dual-energy X-ray absorptiometry (DXA).
Main Results:
- Children who were breastfed exhibited higher bone mineral density at the femoral neck, lumbar spine, and total body compared to bottle-fed children.
- The positive association between breastfeeding and bone mass was significant in children born at term, but not in preterm infants.
- Breastfeeding for less than three months was not associated with increased bone mass.
Conclusions:
- Breastfeeding, particularly for three months or longer, is associated with enhanced bone mass in term-born prepubertal children.
- The findings suggest a potential biological mechanism linking breastfeeding to improved bone development.
- These results highlight the importance of early-life interventions for osteoporosis prevention, potentially starting from infancy.
Abstract:
The aim of this study was to determine whether breastfeeding in early life is associated with bone mass in prepubertal children. We studied 330 8-year-old male and female children from Southern Tasmania representing 47% of those who originally took part in a birth cohort study of risk factors for Sudden Infant Death Syndrome in 1988. Breastfeeding intention and habit were assessed in both 1988 and 1996. Bone mineral density was measured by dual-energy X-ray densitometry. Children who were breastfed had higher bone mineral density at the femoral neck (+0.20 SD, p = 0.07), lumbar spine (+0.25 SD, p = 0.03) and total body (+0.29 SD, p = 0.006) compared with those who were bottle-fed. This association with breastfeeding was present in children born at term (femoral neck: +0.26 SD, p = 0.05; lumbar spine: +0.34 SD, p = 0.007; total body: +0.41 SD, p = 0.0008) but not those born preterm, and remained significant after adjustment for size, lifestyle factors and socioeconomic factors. Breastfeeding for less than 3 months was not associated with increased bone mass at any site. In conclusion, this study has demonstrated a beneficial association between breastfeeding in early life and bone mass in 8-year-old children born at term, particularly those breastfed for 3 months or longer, which appears biological. If this association is confirmed in other populations and persists until the attainment of peak bone mass then the implication would be that osteoporosis prevention programs need to start very early in the life cycle.
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