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Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
Published on: January 12, 2019
Comparison of the Gross Motor Function Measure and Paediatric Evaluation of Disability Inventory in assessing motor
E Nordmark1, G B Jarnlo, G Hägglund
1Institute for Musculoskeletal Diseases, Department of Physical Therapy, University of Lund, Sweden. eva.nordmark@sjukgym.lu.se
Insights
The Pediatric Evaluation of Disability Inventory (PEDI) and Gross Motor Function Measure (GMFM) are valuable for tracking functional changes in children with cerebral palsy (CP) after surgery. PEDI detected changes earlier and in more severe cases than GMFM.
Area of Science:
- Pediatric Rehabilitation
- Neurology
- Clinical Assessment
Background:
- Cerebral palsy (CP) significantly impacts motor function in children.
- Selective dorsal rhizotomy (SDR) combined with physiotherapy is a common intervention for CP.
- Accurate functional outcome measures are crucial for evaluating treatment efficacy.
Purpose of the Study:
- To compare the sensitivity and timing of functional changes detected by the Gross Motor Function Measure (GMFM) and the Pediatric Evaluation of Disability Inventory (PEDI).
- To assess these measures in children with spastic diplegia undergoing SDR and physiotherapy.
- To determine the complementary roles of GMFM and PEDI in evaluating functional recovery.
Main Methods:
- 18 children with spastic diplegia, classified by Gross Motor Function Classification System (GMFCS) into mild and severe impairment groups.
- Functional outcomes assessed using GMFM and PEDI preoperatively and at 6 and 12 months postoperatively.
- Comparative analysis of GMFM and PEDI sensitivity to changes over time within and between severity groups.
Main Results:
- Both GMFM and PEDI detected functional changes over time in the overall cohort and the milder impairment group.
- The PEDI identified significant changes earlier than the GMFM.
- In the more severe impairment group, only the PEDI detected significant functional improvements, while the GMFM did not.
- The findings suggest GMFM and PEDI measure different functional aspects.
Conclusions:
- GMFM and PEDI are complementary functional outcome measures for children with CP post-SDR.
- PEDI demonstrates greater sensitivity in detecting earlier and more significant changes, particularly in children with severe motor impairment.
- These measures are essential for comprehensive assessment of functional recovery in pediatric CP rehabilitation.
Abstract:
This study was designed to compare assessment with the functional outcome measures Gross Motor Function Measure (GMFM) and Pediatric Evaluation of Disability Inventory (PEDI) over time, in children with cerebral palsy (CP) undergoing selective dorsal rhizotomy combined with individualised physiotherapeutic interventions. Using the Gross Motor Function Classification System (GMFCS), 18 children with spastic diplegia were divided into two groups according to age-related severity of motor function impairment. Data were collected preoperatively, and at 6 and 12 months postoperatively. Both instruments were sensitive to changes in function over time in the series as a whole and in the group with milder impairment, although the PEDI detected significant changes earlier. In the group with more severe impairment, changes in function were detected only with the PEDI, not with the GMFM. Thus, the instruments are to be considered complementary tests, because they measure different aspects of function.
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