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Cerebellar abnormalities in mental illness. A study on Purkinje cell density in schizophrenic men
B Lingärde1, S A Jönsson, A Luts
1Department of Clinical Neuroscience, University Hospital, Lund.
European Child & Adolescent Psychiatry
|May 5, 2000
Abstract:
The linear Purkinje cell density in the cerebellar vermis was investigated in a small cohort of adult onset schizophrenic men with well-documented hippocampal abnormalities. There were no differences in comparison with age-matched controls. This negative finding indicates that vermian abnormalities undoubtedly seen in some schizophrenic patients may constitute a subsyndrome, possibly related to autistic disorders in which cerebellar abnormalities are well corroborated.