Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optimized MR imaging for polyacrylamide gel dosimetry.

I C Baustert1, M Oldham, T A Smith

  • 1CRC Clinical Magnetic Resonance Research Group, The Institute of Cancer Research, The Royal Marsden NHS Trust, Sutton, Surrey, UK.

Physics in Medicine and Biology
|May 5, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evidence for the Collective Nature of Radial Flow in Pb+Pb Collisions with the ATLAS Detector.

Physical review letters·2026
Same author

Evidence for the Dimuon Decay of the Higgs Boson in pp Collisions with the ATLAS Detector.

Physical review letters·2025
Same author

Asthma Exacerbations Requiring ICU: Risk Factors and Challenges in Management.

Irish medical journal·2025
Same author

Evidence for Longitudinally Polarized W Bosons in the Electroweak Production of Same-Sign W Boson Pairs in Association with Two Jets in pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

Physical review letters·2025
Same author

Conservative management of perforation of a duodenal diverticulum.

Irish medical journal·2025
Same author

Observation of tt[over ¯] Production in Pb+Pb Collisions at sqrt[s_{NN}]=5.02  TeV with the ATLAS Detector.

Physical review letters·2025
Same journal

Effective contrast-enhanced preprocessing for intracranial artery segmentation in digital subtraction angiography.

Physics in medicine and biology·2026
Same journal

Improving Plan Quality in Adaptive Proton Therapy Using an Interactive Dose Modification Tool.

Physics in medicine and biology·2026
Same journal

Technical Note: Real-Time MLC Control and Latency Measurement Optimization with External Verification.

Physics in medicine and biology·2026
Same journal

Fetus-Specific Hematopoietic Stem Cell Dosimetry Framework for Leukemia-Relevant Target Cells During Prenatal Development.

Physics in medicine and biology·2026
Same journal

Deep learning-based dose prediction to enhance planning efficiency in cervical brachytherapy with hybrid applicators.

Physics in medicine and biology·2026
Same journal

Corrigendum: Referenceless MR thermometry-a comparison of five methods (2017<i>Phys. Med. Biol</i>.<b>62</b>1-16).

Physics in medicine and biology·2026
See all related articles

Accurate measurement of polyacrylamide gel dosimetry is crucial for clinical radiotherapy. This study optimizes Magnetic Resonance (MR) imaging sequences, finding multiple spin echo sequences provide the most accurate T2 relaxation time measurements.

Area of Science:

  • Medical Physics
  • Radiotherapy Dosimetry

Background:

  • Polyacrylamide gels are sensitive to radiation, enabling dose measurement via Nuclear Magnetic Resonance (NMR) T2 relaxation times.
  • Accurate mapping of T2 values is essential for clinical radiotherapy applications of these dosimeters.

Purpose of the Study:

  • To optimize Magnetic Resonance (MR) imaging techniques for accurate and practical measurement of T2 values in polyacrylamide gel dosimeters.
  • To evaluate different MR imaging sequences for their suitability in gel dosimetry.

Main Methods:

  • Comparison of four MR imaging sequences to measure T2 relaxation times in polyacrylamide gels.
  • Analysis of accuracy, signal-to-noise ratio, and acquisition time for each sequence.
  • Focus on T2 values typical for gel dosimeters (140-700 ms).

Related Experiment Videos

Main Results:

  • Multiple spin echo sequences achieved the highest accuracy (98.9%) in measuring gel T2 values.
  • Single spin echo sequences (Hahn, EPI) measured gel T2 values with 90.1% accuracy.
  • Optimization of MR imaging parameters is critical for reliable dosimetry.

Conclusions:

  • Careful selection and optimization of MR imaging sequences are paramount for accurate and reliable polyacrylamide gel dosimetry.
  • Multiple spin echo sequences are recommended for precise T2 value measurements in this application.