Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interventions for emergency contraception.

L Cheng1, A M Gülmezoglu, E Ezcurra

  • 1UNDP/UNFPA/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Reproductive Health and Research, World Health Organization, 1211-Geneva 27, SWITZERLAND. gulmezoglum@who.ch

The Cochrane Database of Systematic Reviews
|May 5, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Mangrove preservation could have significantly reduced damages from Hurricane Otis on the coast of Guerrero, Mexico" [Sci. Total Environ. (2024), 177822].

The Science of the total environment·2025
Same author

Mangrove preservation could have significantly reduced damages from Hurricane Otis on the coast of Guerrero, Mexico.

The Science of the total environment·2024
Same author

Maternal characteristics and causes associated with refractory postpartum haemorrhage after vaginal birth: a secondary analysis of the WHO CHAMPION trial data.

BJOG : an international journal of obstetrics and gynaecology·2019
Same author

Diagnostic accuracy of the partograph alert and action lines to predict adverse birth outcomes: a systematic review.

BJOG : an international journal of obstetrics and gynaecology·2019
Same author

A natural experiment reveals the impact of hydroelectric dams on the estuaries of tropical rivers.

Science advances·2019
Same author

Global inequities in dietary calcium intake during pregnancy: a systematic review and meta-analysis.

BJOG : an international journal of obstetrics and gynaecology·2018

Levonorgestrel and mifepristone are effective emergency contraceptive methods. Levonorgestrel shows higher efficacy and fewer side effects than the Yuzpe regimen, but mifepristone may be more effective in some cases.

Area of Science:

  • Reproductive Health
  • Pharmacology

Background:

  • Emergency contraception is crucial for preventing unintended pregnancies after unprotected intercourse.
  • Various methods exist, necessitating a comparison of their efficacy and safety.

Purpose of the Study:

  • To identify the most effective, safe, and convenient emergency contraceptive method for preventing pregnancy post-intercourse.

Main Methods:

  • Systematic review of randomized or quasi-randomized trials on emergency contraception.
  • Searches included multiple databases and contact with researchers and pharmaceutical companies.
  • Data extraction and analysis were performed in duplicate using fixed-effects models.

Main Results:

  • Levonorgestrel demonstrated higher effectiveness and fewer side effects compared to the Yuzpe regimen.

Related Experiment Videos

  • Mifepristone showed higher efficacy than levonorgestrel in one study, though effectiveness varied by dose.
  • Delayed menses were associated with higher mifepristone doses.

    • Conclusions:

    • Levonorgestrel and mifepristone offer high efficacy with acceptable side effect profiles.
    • Low-dose mifepristone minimizes menstrual delay without compromising effectiveness.
    • Further research is recommended to directly compare mifepristone and levonorgestrel effectiveness.