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Updated: Aug 12, 2026
14:54
Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
Published on: November 29, 2015
[Anterior ischemic optic neuropathy in children]
1División de Neurología Pediátrica, New York Presbyterian Hospital, NY 10021, USA.
Revista De Neurologia
|May 8, 2000
Summary
A child on peritoneal dialysis developed sudden bilateral blindness due to anterior ischemic optic neuropathy. Prompt treatment did not restore vision, highlighting the severity of this condition in pediatric patients.
Area of Science:
- Ophthalmology
- Nephrology
- Pediatrics
Background:
- A 5-year-old girl with chronic renal failure from congenital kidney disease underwent peritoneal dialysis.
- She experienced asymptomatic arterial hypotension post-dialysis.
Observation:
- The patient presented with sudden, severe bilateral blindness, including absent light perception and unresponsive pupils.
- Ophthalmoscopy revealed pale optic discs and abnormal retinal vasculature.
- Neurological and MRI evaluations were unremarkable.
Findings:
- The final diagnosis was anterior ischemic optic neuropathy.
- Despite treatment with corticosteroids, antibiotics, and antivirals, vision loss was permanent.
Implications:
- This case underscores the risk of anterior ischemic optic neuropathy in children with chronic kidney disease and peritoneal dialysis.
- Early recognition and management are crucial, though outcomes can be poor.
- Further research into pathogenesis and preventative strategies is warranted.
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