Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Congenital tuberculosis.

S Balasubramanian1, R Shivram, L N Padmasani

  • 1Department of Paediatrics, Sri Ramachandra Medical College, Porur, Chennai.

Indian Journal of Pediatrics
|May 8, 2000
PubMed
Summary

Congenital tuberculosis in an infant, confirmed by acid-fast bacilli in gastric aspirates, highlights the importance of maternal investigation. Maternal endometrial biopsy confirmed tuberculosis, underscoring its role in diagnosing infant cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inclusive Search for Anomalous Single-Photon Production in MicroBooNE.

Physical review letters·2026
Same author

Navigating the Challenges of Implementing Tuberculosis Research During COVID-19 Pandemic: Insights from the Pediatric Tuberculosis-Moderate Acute Malnutrition Study.

Indian pediatrics·2026
Same author

First Search for Dark Sector e^{+}e^{-} Explanations of the MiniBooNE Anomaly at MicroBooNE.

Physical review letters·2026
Same author

First Measurement of Charged-Current Muon-Neutrino-Induced K^{+} Production on Argon Using the MicroBooNE Detector.

Physical review letters·2026
Same author

Scarlet fever - A retrospective case series in the midst of recent upsurge of cases in India.

Indian journal of medical microbiology·2025
Same author

Search for an Anomalous Production of Charged-Current ν_{e} Interactions without Visible Pions across Multiple Kinematic Observables in MicroBooNE.

Physical review letters·2025

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Neonatology

Background:

  • Congenital tuberculosis is a rare but severe neonatal infection.
  • Early diagnosis and treatment are crucial for infant survival.
  • Maternal tuberculosis is the primary source of congenital infection.

Observation:

  • A 29-day-old infant presented with fever, cough, respiratory distress, and abdominal distension.
  • Clinical examination revealed failure to thrive, tachypnea, pallor, and hepatosplenomegaly.
  • Chest X-ray showed extensive broncho-pneumonic changes.

Findings:

  • Gastric aspirate smears revealed acid-fast bacilli (AFB), and culture confirmed Mycobacterium tuberculosis.
  • Maternal endometrial biopsy demonstrated tuberculous granuloma and AFB.
  • Culture of endometrial aspirate also yielded Mycobacterium tuberculosis.

Implications:

  • This case underscores the critical need for maternal endometrial biopsy in diagnosing congenital tuberculosis.
  • Investigating the mother is essential when congenital tuberculosis is suspected in an infant.
  • Prompt diagnosis and treatment based on maternal evaluation can improve infant outcomes.

Related Experiment Videos