[Pathology of acute and chronic tendon injuries]
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Updated: Oct 16, 2026

Engineering Tendon Assembloids to Probe Cellular Crosstalk in Disease and Repair
Published on: March 22, 2024
1Orthopädische Klinik, Medizinische Hochschule im Annastift e.V., Hannover. wirth@annastift.de
Abstract:
The load limit of a tendon is expressed by the not linear force/lengthening behavior. It is determined by the interrelation between load and load-bearing capacity. The load of a tendon results from exogenous, endogenous and temporal factors. The property factors and the aging influence the load-bearing capacity of a tendon. Partial ruptures show necrosis, calcification and fiber swelling. The attachment area shows a mineralization of the cartilage zone, a loss of the collagen fibrils and calcifications. The tendon rupture knows extrinsic and intrinsic causes. Primary are micro and macrovascular tendon alterations, usually favour the rupture of tendons.
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