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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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Feedback induction of suppressor T-cell activity

D D Eardley, R K Gershon

    The Journal of Experimental Medicine
    |August 1, 1975
    PubMed

    Adoptively transferred carrier immune T cells interact with nonimmune T cells in recipients in a fashion which generates specific immunosuppression although both the immune and normal cells function quite well as helper cells when not admixed.

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