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Mycotic keratitis by Fusarium. A review and report of two cases
Abstract:
World literature on the subject reports 112 cases of keratomycosis by Fusarium, including the two cases described in this paper and some personal communications. In most of these cases (60--70%) there is a history of trauma inflicted by vegetable matter or by foreign bodies introduced into the eye (metal, sand, stone, etc.). The different species of Fusarium isolated are F. episphaeria, F. dimerum, F. moniliforme, F. nivale, F. oxysporum, and F. solani. The treatment recommended in a 5-percent suspension or unguent of pimaricin (natamycin).
Insights
Fusarium keratomycosis, a fungal eye infection, often follows eye trauma from vegetable matter or foreign bodies. Pimaricin (natamycin) is the recommended treatment for this serious condition.
Area of Science:
- Ophthalmology
- Mycology
- Infectious Diseases
Background:
- Keratomycosis, a fungal infection of the cornea, poses a significant threat to vision.
- Fusarium species are common causative agents, particularly after ocular trauma.
- A review of global literature identified 112 cases of Fusarium keratomycosis.
Purpose of the Study:
- To analyze the incidence and characteristics of Fusarium keratomycosis.
- To identify risk factors associated with Fusarium keratomycosis.
- To review recommended treatment protocols for Fusarium keratomycosis.
Main Methods:
- Literature review of reported Fusarium keratomycosis cases.
- Analysis of clinical data from personal communications and published studies.
- Identification of Fusarium species involved in keratomycosis.
Main Results:
- Fusarium keratomycosis is frequently linked to ocular trauma (60-70% of cases).
- Common inciting factors include vegetable matter, metal, sand, and stones.
- Isolated Fusarium species include F. episphaeria, F. dimerum, F. moniliforme, F. nivale, F. oxysporum, and F. solani.
Conclusions:
- Prompt diagnosis and treatment are crucial for managing Fusarium keratomycosis.
- Pimaricin (natamycin) is the established therapeutic agent.
- Understanding causative agents and risk factors aids in prevention and treatment strategies.