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[Roaming through methodology. XVIII. Selection of control groups].

M A van den Bosch1, B C Tanis, J M Kemmeren

  • 1Universitair Medisch Centrum, Julius Centrum voor Patiëntgebonden Onderzoek, Utrecht. m.vandenbosch@jc.azu.nl

Nederlands Tijdschrift Voor Geneeskunde
|May 9, 2000
PubMed
Summary

Selecting appropriate control groups is crucial for case-control studies. Random-digit dialing offers a practical method for recruiting population controls, especially when registries are unavailable.

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Area of Science:

  • Epidemiology
  • Biostatistics

Context:

  • Case-control studies are fundamental in epidemiological research for investigating disease etiology.
  • The validity of case-control study findings heavily relies on the appropriate selection of control groups.
  • Various control group selection methods exist, each with inherent strengths and weaknesses.

Purpose:

  • To discuss the importance and methods of selecting valid control groups in case-control studies.
  • To highlight the advantages and disadvantages of different control group types, including population controls, hospital controls, and surrogate controls.
  • To introduce random-digit dialing as a viable technique for recruiting population controls.

Summary:

  • The choice of control group significantly impacts the validity of case-control studies.

Related Experiment Videos

  • Available control group options include population-based, hospital-based, and convenience samples (e.g., friends/relatives).
  • Random-digit dialing presents an effective strategy for obtaining population controls via telephone, particularly useful in the absence of existing registries.

    • Impact:

    • Provides guidance for researchers on selecting appropriate control groups to enhance study rigor.
    • Offers a practical solution for control group recruitment in epidemiological research, especially in resource-limited settings.
    • Contributes to the methodological discussion in epidemiologic literature regarding control selection strategies.