Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Late ventricular structure after partial left ventriculectomy.

P P Lunkenheimer1, K Redmann, C W Cryer

  • 1University Hospital and Institute of Numerical Mathematics, Münster, Germany. redmann@uni-muenster.de

The Annals of Thoracic Surgery
|May 9, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lack of evidence for longitudinal dissociation of the atrioventricular conduction axis.

Clinical anatomy (New York, N.Y.)·2023
Same author

The initial maturation status of marmoset testicular tissues has an impact on germ cell maintenance and somatic cell response in tissue fragment culture.

Molecular human reproduction·2020
Same author

[The antagonistic function of the heart muscle sustains the autoregulation according to Frank and Starling : Part I: Structure and function of heart muscle].

Herz·2018
Same author

[Antagonistic function of the heart muscle : Part II: Clinical implications].

Herz·2018
Same author

Raman micro-spectroscopy analysis of different sperm regions: a species comparison.

Molecular human reproduction·2018
Same author

Reassembly of adult human testicular cells: can testis cord-like structures be created in vitro?

Molecular human reproduction·2018

A patient died from heart failure after surgery due to malaligned heart muscle fibers around the ventricular scar. This misalignment caused compression and tissue death, impacting cardiac function.

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Pathology
  • Histopathology

Background:

  • Partial ventriculectomy is a surgical procedure to reduce heart size and improve function in conditions like dilated cardiomyopathy.
  • Post-surgical complications, including progressive heart failure, can occur despite surgical intervention.
  • Understanding the structural changes in cardiac tissue following surgery is crucial for improving patient outcomes.

Observation:

  • A 53-year-old male patient experienced progressive heart failure nine months post-partial ventriculectomy.
  • Autopsy revealed an 11 cm long ventricular scar extending beyond the suture line.
  • Microscopic examination showed malalignment of muscle fibers in the middle and subendocardial layers surrounding the scar.

Findings:

  • The malaligned muscle fibers converged and were compressed within the scar tissue.

Related Experiment Videos

  • This structural abnormality led to regional myocardial necrosis (tissue death).
  • The extent of scar tissue and fiber malalignment correlated with the patient's fatal heart failure.

    • Implications:

    • Surgical techniques should aim to minimize scar tissue formation and preserve muscle fiber alignment.
    • Further research into the biomechanics of ventricular scars is needed.
    • Histopathological analysis can reveal critical insights into post-surgical cardiac remodeling and failure.