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Updated: Oct 16, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
[Renal cell carcinoma associated with renal angiomyolipoma and renal cortical adenoma]
J Bragagnolo1, H Damiani, J Ferrer
1Departamento de Urología, Sanatorio Parque, Rosario, Argentina.
Objective:
To report a case of renal cell carcinoma associated with renal angiomyolipoma and renal cortical adenoma and discuss the possibility of a hereditary etiology.
Methods:
A 64-year-old patient with a tumor in the right kidney underwent right renal nephrectomy. The pathological findings revealed a clear cell renal carcinoma, two cortical angiomyolipoma and a renal cortical adenoma. The literature on these three coincident renal tumors is reviewed.
Results:
The association of these three renal tumors is rare and is usually seen in patients with tuberous sclerosis.
Conclusions:
Renal angiomyolipoma is a benign tumor frequently associated with Bourneville's disease or tuberous sclerosis, a disorder of autosomal dominant transmission. Familial evidence of renal cell carcinoma has been previously reported, as in von Hippel-Lindau disease. It has been suggested that heredity may play an important role in the association of renal cell carcinoma and other renal tumors.
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