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A rare pituitary lesion.

S Basaria¹, A R Ayala, C Guerin

¹Division of Endocrinology and Metabolism, Johns Hopkins University, Baltimore 21287, USA.

Journal of Endocrinological Investigation

|May 10, 2000

Summary

Tuberculous hypophysitis, a rare pituitary infection, can mimic pituitary adenomas. This case highlights a Sudanese woman with a pituitary mass initially presumed to be an adenoma, later diagnosed as tuberculosis.

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Area of Science:

Endocrinology
Infectious Diseases
Neuropathology

Background:

Sellar masses are predominantly pituitary adenomas.
Non-adenomatous hypophyseal lesions, including granulomatous hypophysitis, are uncommon.
Granulomatous hypophysitis can result from infections like tuberculosis.

Observation:

A Sudanese woman presented with a pituitary mass, clinically suspected to be an adenoma.
The patient underwent trans-sphenoidal surgery for the sellar mass.
Post-operative histopathology revealed tuberculous hypophysitis.

Findings:

The patient had no prior history of tuberculosis or disseminated infection.
This case represents a rare instance of isolated pituitary tuberculosis.
Literature review on pituitary tuberculomas is included.

Implications:

Tuberculous hypophysitis should be considered in the differential diagnosis of sellar masses, even without a history of tuberculosis.
Early diagnosis and appropriate treatment are crucial for managing this rare condition.
This case underscores the importance of histopathological examination for definitive diagnosis of pituitary lesions.

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